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The Cream - Sample

Moisturising and Anti-ageing with GSM10® and ProGR3® | 0,1 fl.oz | 3 ml

Key Points

- 99% from natural origin

- Exclusive patented active compounds (patent deposited)

- Proven results

- Dermatologically tested

- Vegan

- Gender neutral

- For all skin types

- Mostly recyclable                   

- Packaging made of paper from responsible FSC® certified paper


The Serum from Le Domaine is made of science and terroir. It contains a very high concentration of GSM10® (50% higher than the creams) and ProGR3®, two exclusive patented active compounds* that slow down the signs of skin ageing. It is also formulated with hydrating and soothing grape water. It is enriched with two vine flower sister cells, with complexion perfecting and skin beautifying effectiveness. It contains hyaluronic acids with wrinkle-smoothing and moisturising effects. Its ultra-silky texture is well absorbed and leaves the skin intensely plumped up. From the first use, the serum gives the skin a boost effect, the skin is unified, the skin texture refined.After  28 days of use, it has an anti-wrinkle and a global anti-ageing effect: revitalized and protected, the skin is smoother, firmer and more beautiful, it regains its radiance and looks visibly younger.                     

*patents deposited

Test Results

Moisturising: The Serum is an excellent moisturizer at short, mid and long term. 100% of subjects have an improvement in hydration level                                 

Antioxidant: The antioxidant efficacy of The Serum was measured by in vitro test                             

Anti-ageing: Clinical scoring tests carried out during use test conducted under dermatological control have shown that after 28 days of use The Serum is significantly anti-wrinkle, has an anti-fatigue and plumping effect, and improves the radiance of the complexion and the glow 

Use tests: From the first use

- 84% find that the skin is unified and the skin texture refined

- 82% find that the Serum boosts the skin's energy.

After 28 days of use

- 94% find that their complexion is more luminous

- 97% that their skin is smoother

- 91% that their skin is firmer and more toned

- 94% find that their skin is soothed and is more beautiful.            

In vivo clinical test carried out under dermatological control on a panel of 32 women and men aged between 40 and 65 years.

Active Compounds

GSM10®: Resulting from more than 10 years of research on grape marcs of the Perrin Family carried out with Professor Teissedre of the University of Bordeaux, specialized in research topics related to the phenolic compounds of grapes and vines. Following the characterisation of all Perrin grape varieties, he formulated GSM10® with proven anti-oxidant and anti-ageing properties (anti-MMPs - matrix metalloproteinases such as collagenase action). It also contributes to improving the balance of the skin (postbiotic action)

ProGR3®: Resulting from the research conducted by professor Nicolas Lévy and Professeur Pierre Cau on progeria, a rare genetic disease that causes accelerated ageing of children. They have identified the mechanisms involved in progeria and have transferred their expertise on the creation of a patented (patent deposited) cosmetic active ingredient: the ProGr3®.  Its effectiveness has been proven on reducing the toxicity of progerin, the senescence marker protein and slowing down the signs of ageing

Organic Grape Water: base of the formulation of The Serum, this grape water from organic farming is known for its soothing and moisturizing properties

Sister cells of vine flowers: obtained by biotechnology, this active ingredient has been integrated into the Serum formula at a high concentration for its energizing, protective and perfecting action. It has a proven efficacy on the perfection of the complexion and the beautification of the skin

Hyaluronic acids: selected from different molecular weights for complementary hydrating and anti-wrinkle action                                    


Ingrédients: Vitis Vinifera (Grape) Fruit Water*, Aqua (Water), Glycerin, Pentylene Glycol, Diglycerin, Propanediol, Lauroy Lysine, Vitis Vinifera (Grape) Flower Cell Extract, Caesalpinia Spinosa Fruit Extract, Centella Asiatica Leaf Extract, Chondrus Crispus (Carrageenan) Extract, Microcrystalline Cellulose, Vitis Vinifera (Grape) Skin Extract*, Vitis Vinifera (Grape) Vine Extract, Xanthan Gum, Sodium Gluconate, Kappaphycus Alvarezii Extract, Glucose, Cellulose Gum, Citric Acid, Hydrolyzed Hyaluronic Acid, O-Cymen-5-Ol, Potassium Sorbate, Sodium Benzoate, Tamarindus Indica Seed Gum, Sodium Hyaluronate, Sodium Hydroxyde, Andrographis Paniculata Leaf Extract, Lactobacillus Ferment, Camellia Sinensis Leaf Extract, Chamomilla Recutita (Matricaria) Flower Extract.

* ingredients from organic farming

This list of ingredients may be subject to change, please consult the packaging of the product purchased. 

Use Guidance

Apply morning and/or evening onto clean face and neck